Metoclopramidum [Inn-Latin]

Metoclopramidum [Inn-Latin] Brand names, Metoclopramidum [Inn-Latin] Analogs

Metoclopramidum [Inn-Latin] Brand Names Mixture

No information avaliable

Metoclopramidum [Inn-Latin] Chemical_Formula

C₁₄H₂₂ClN₃O₂

Metoclopramidum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic2/metoclo.htm

Metoclopramidum [Inn-Latin] fda sheet

Metoclopramidum_[Inn-Latin] FDA

Metoclopramidum [Inn-Latin] msds (material safety sheet)

Metoclopramidum_[Inn-Latin] MSDS

Metoclopramidum [Inn-Latin] Synthesis Reference

Thominet, U.S. Pat. 3,177,252 (1965)

Metoclopramidum [Inn-Latin] Molecular Weight

299.796 g/mol

Metoclopramidum [Inn-Latin] Melting Point

147.25 ^oC

Metoclopramidum [Inn-Latin] H₂O Solubility

200 mg/L

Metoclopramidum [Inn-Latin] State

Solid

Metoclopramidum [Inn-Latin] LogP

2.464

Metoclopramidum [Inn-Latin] Dosage Forms

Liquid; Syrup; Tablet

Metoclopramidum [Inn-Latin] Indication

For the treatment of gastroesophageal reflux disease (GERD)

Metoclopramidum [Inn-Latin] Pharmacology

Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.

Metoclopramidum [Inn-Latin] Absorption

Rapidly and well absorbed (oral bioavailability 80±15.5%).

Metoclopramidum [Inn-Latin] side effects and Toxicity

Oral, mouse LD₅₀: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.

Metoclopramidum [Inn-Latin] Patient Information

Metoclopramidum [Inn-Latin] Organisms Affected

Humans and other mammals